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Product introduction
SKI V 是一种非竞争性的,有效的非脂质鞘氨醇激酶 (SPHK; SK) 抑制剂,对 GST-hSK 的 IC50 为 2 μM。 SKI V 有效抑制 PI3K,对 hPI3k 的 IC50 为 6 μM。SKI V 减少有丝分裂的第二信使鞘氨醇-1-磷酸 (S1P) 的形成。SKI V 诱导细胞凋亡 (apoptosis) 并具有抗肿瘤活性。 Information SKI-V SKI V is a noncompetitive and potent inhibitor of non-lipid sphingosine kinase with IC50 of 2 μM for GST-hSK. SKI-V also inhibits PI3K with IC50 of 6 μM for hPI3k . SKI-V decreases formation of the mitogenic second messenger sphingosine-1-phosphate (S1P) and induces apoptosis with antitumor activity.
Chinese name
SKI-V
English name
SKI-V
Chinese alias
-
English alias
2-​[(3,​4-​dihydroxyphenyl)​methylene]​-3(2H)​-​Benzofuranone
CAS number
24418-86-8
molecular formula
C15H10O4
molecular weight
254.24 g/mol
Exact mass
≥99%
PSA
66.800 Ų
Logp
2.900
Technical Documents
「No technical documents」
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SKI-V 98% 25mg

Yuanye SKI-V 98% 25mg, CAS 24418-86-8, complete specifications; suitable for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.

item number:Y69232-25mg
Product model:25mg
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Lead Time:30days
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