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Product introduction

Z-Ala-Ala-Asn-AMC (Cbz-Ala-Ala-Asn-AMC) is the legumain substrate. Overexpressed legumain in 293 HEK-Leg cells potently cleaved CBZ-Ala-Ala-Asn-AMC. In Vitro The first legumain fluorogenic substrate Cbz-Ala-Ala-Asn-AMC based on the P3-P2-P1 sequence Ala-Ala-Asn. The synthetic substrate Cbz-Ala-Ala-Asn-AMC is effectively cleaved by S. mansoni legumain and human legumain with K m s of 90 and 80 uM respectively . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid

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Chinese name

Z-Ala-Ala-Asn-AMC

English name

Z-Ala-Ala-Asn-AMC

Chinese alias

丙氨酸-丙氨酸-天冬氨酸-AMC

English alias

CAS number

149697-16-5

molecular formula

C28H31N5O8

molecular weight

565.57 g/mol

Exact mass

≥99%

PSA

Logp

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