胰蛋白酶 来源于人类胰腺

np001008-25μg

25μg

生物活性

≥95%(SDS-PAGE)

水解涉及 L - 精氨酸或 L - 赖氨酸羧基的肽键、酰胺键与酯键。研究发现，囊性纤维化（cystic fibrosis）患者体内该酶及其酶原（胰蛋白酶原，trypsinogen）的血清水平会升高。胰蛋白酶原存在三种亚型，分别是阳离子型（胰蛋白酶原 1，trypsinogen 1）、阴离子型（胰蛋白酶原 2，分子量 22,500）和中胰蛋白酶原（胰蛋白酶原 3，分子量 25,000）。 本品为阳离子型。 本产品由特定组织制备而成，该组织经美国食品药品监督管理局（FDA）要求的检测证实，乙型肝炎表面抗原（HBsAg）、丙型肝炎抗体（anti-HCV）、乙型肝炎核心抗体（anti-HBc）检测结果均为阴性，1 型和 2 型人类免疫缺陷病毒抗体（anti-HIV 1 & 2）检测结果也为阴性。 阿拉丁（Aladdin）产品均为实验室试剂，不得用于人体给药，也不得用于任何药物相关用途。仅限科研或进一步生产使用。 Hydrolyzes peptides, amides, and ester bonds involving the carboxyl groups of L-arginine or L-lysine. Increased serum values of this enzyme and/or its zymogen (trypsinogen) have been found in patients with cystic fibrosis. Trypsinogen has three isoforms: cationic (trypsinogen 1), anionic (trypsinogen 2, MW 22,500), and mesotrypsinogen (trypsinogen 3, MW, 25,000). This product is the cationic form. Prepared from tissue shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA-required tests. Aladdin products are laboratory reagents and are not to be administered to humans or used for any drug purpose. For research or further manufacturing use only.

Vitronectin is a cell adhesion and spreading factor found in serum and tissues. Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. Inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway.Somatomedin-B is a growth hormone-dependent serum factor with protease-inhibiting activity. Post-translational: Sulfated on tyrosine residues. N- and O-glycosylated. Phosphorylation on Thr-69 and Thr-76 favors cell adhesion and spreading.It has been suggested that the active SMB domain may be permitted considerable disulfide bond heterogeneity or variability, thus two alternate disulfide patterns based on 3D structures are described with 1 disulfide bond conserved in both.Phosphorylation sites are present in the extracellular medium.

≥2.5 U/mg protein

天然

21-23 kDa

人(Human)