免疫球蛋白G,Fab'2,人血浆

np001072-250μg

250μg

≥95%(SDS-PAGE)

F(ab’) 2相对于抗原结合位点是二价的。它缺少IgG分子的Fc区，使其成为抗体研究中的一种有价值的工具，在抗体研究中，Fc区的结合是不可取的。此外，当使用低亲和力抗体时，鉴于其较高的结合常数，二价F（ab'）2比单价Fab或Fab'片段更可取。 由经美国食品药品监督管理局要求的测试显示对HBsAg、抗-HCV、抗-HBc无反应且对抗-HIV 1和2呈阴性的血浆制备。 Ref.: Lamoyi, Edmundo. 1985. Methods in Enymology 121, 62. F(ab’)2 is bivalent in relation to the antigen binding sites. It lacks the Fc region of the IgG molecule, making it a valuable tool in antibody studies in which binding of the Fc region is not desireable. In addition, when working with low affinity antibodies, bivalent F(ab’)2 is preferable to univalent Fab or Fab’ fragments given its higher association constant. Prepared from plasma shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA-required tests. Ref.: Lamoyi, Edmundo. 1985. Methods in Enymology 121, 62.

110000