防御素,α，混合自人中性粒细胞（HNP，人中性粒细胞肽）

np001100-25μg

25μg

≥95%(SDS-PAGE)

一般来说，防御素是脊椎动物和无脊椎动物中发现的富含半胱氨酸的小阳离子蛋白。这些混合的α-防御素是从人类中性粒细胞中纯化出来的。这些肽在杀死细菌、真菌和包膜病毒方面具有活性，因此使中性粒细胞能够灭活和破坏潜在的病原体。防御素通过电吸引穿透微生物的细胞膜，从而在膜上形成孔隙，从而损伤或杀死摄入的微生物。 对于0.1%的溶液，使用2.95的消光系数来测定蛋白质浓度。 In general, defensins are small cysteine-rich cationic proteins found in both vertebrates and invertebrates. These mixed alpha defensins are purified from human neutrophils. These peptides are active in killing bacteria, fungi, and enveloped viruses, and therefore, enable the neutrophils to inactivate and destroy potential pathogens. Defensins damage or kill ingested microbes by penetrating the microbial's cell membrane by way of electrical attraction, and consequently forming pores in the membrane. Protein concentration is determined using an extinction coefficient of 2.95 for a 0.1% solution. Product Citation: Maeda T, Sakiyama T, Kanmura S, Hashimoto S, et al. Low concentrations of human neutrophil peptide ameliorate experimental murine colitis. Int J Mol Med. 2016 Dec;38(6):1777-1785. Doi: 10.3892/ijmm.2016.2795. Epub 2016 Nov 3.

<3,500