丁酰胆碱酯酶 来源于人血浆

Acylcholine acylhydrolase, BChE | 假性胆碱酯酶 | 胆碱酯酶 | 丁酰基 | 酰基胆碱酰基水解酶

Acylcholine acylhydrolase | BChE

np001121-2U

2U

生物活性

≥90%(SDS-PAGE)

Butyrylcholinesterase (BChE) is a tetrameric glycoprotein belonging to the family of serine hydrolases known as cholinesterases. While there is currently no know physiological function for BChE, it has been shown to behave as a bioscavenger against cocaine toxicity and organophosphorus nerve agents. Prepared from plasma shown to be non reactive for HbsAG, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA-required tests.

Esterase with broad substrate specificity. Contributes to the inactivation of the neurotransmitter acetylcholine. Can degrade neurotoxic organophosphate esters. Post-translational: N-glycosylated. No other PTM detected. The major N-glycan structures are of the complex diantennary type with 1 and 2 N-acetylneuraminic acid molecules (Neu5Ac) making up approximately 33% and 47% of the total N-glycans, respectively. Only low amounts of fucosylated diantennary N-glycans are detected (approximately 2%). Triantennary N-glycans with or without fucose amount to approximately 13%, whereas 5% of the total N-glycans are of the oligomannosidic or hybrid type.

≥50 U/mg protein

天然

340 kDa

人(Human)