载脂蛋白AIV,人血浆

np001136-10μg

10μg

Extinction Coefficient: 1.0

Buy Purified Native Human Apolipoprotein A4 (ApoA4), Human Plasma. Bulk Qty Available. Apolipoprotein AIV (Apo AIV), is a major component of HDL and chylomicrons, is actively synthesized in the small intestine during fat absorption and incorporated onto the surface of nascent chylomicrons that are then secreted into lymph. When these chylomicrons enter plasma, Apo-AIV dissociates from the surface and is found primarily in the lipoprotein-free fraction. Apo AIV may play a role in the secretion and catabolism of chylomicrons and VLDL. It is required for efficient activation of lipoprotein lipase by ApoC-II and is a potent activator of LCAT. Apo AIV is an amphipathic protein that can emulsify lipids and has been linked to protective roles against cardiovascular disease and obesity. Ref: Weinburg, R.B. and Scanu, A. M. J Lipid Res 1983. 24, 52. Dieplinger, H. Menzel, H-J., and Utermann, G. 1992. Lipoprotein Analysis A Practical Approach. (CA Converse and ER Skinner, eds), 43. Prepared from plasma shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests.

46000