α2-HS糖蛋白 来源于人血浆

np001159-50μg

50μg

BioReagent

≥90%(SDS-PAGE)

在人血清中的含量为 60 毫克 / 100 毫升。这种蛋白质是一种负性急性期反应蛋白。临床上，癌症患者体内该蛋白质的浓度会降低。α2-HS 糖蛋白（AHSG）水平与妊娠糖尿病呈正相关，与新生儿骨骼发育呈负相关。研究表明，子宫内膜异位症患者的腹腔液中 α2-HS 糖蛋白浓度较高。 消光系数： 0.703 所用血浆经 FDA 要求的检测显示，乙型肝炎表面抗原（HBsAg）、抗丙型肝炎病毒（抗 - HCV）、抗乙型肝炎核心抗体（抗 - HBc）均为阴性，且抗人类免疫缺陷病毒 1 型和 2 型（抗 - HIV 1 & 2）也为阴性。 Found in human serum at 60 mg per 100 ml. This protein is a negative acute-phase reactant. Clinically, concentrations are reduced in cancer patients. AHSG levels are positively correlated with gestational diabetes and negatively correlated with neonatal skeletal development. Studies show AHSG to be present at high concentrations in the peritoneal fluids of patients with endometriosis. Extinction Coefficient: 0.54 Prepared from plasma shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests.

Promotes endocytosis, possesses opsonic properties and influences the mineral phase of bone. Shows affinity for calcium and barium ions. Post-translational: Phosphorylated by FAM20C in the extracellular medium. O- and N-glycosylated. O-glycosylated with core 1 or possibly core 8 glycans. N-glycan at Asn-156: Hex5HexNAc4; N-glycan heterogeneity at Asn-176: Hex5HexNAc4 (major) and Hex6HexNAc5 (minor).

天然

49 kDa

人(Human)