α1-酸性糖蛋白(A1AGP)

AGP, Orosomucoid | α₁-酸性糖蛋白，人血浆 | α₁-AG | C-AGP | 血清类粘蛋白 | α₁M-血清粘蛋白 | α1 -酸性糖蛋白来源于人类血浆

α - acidic glycoprotein, human plasma | α₁-AG | C-AGP | Serum mucin | α ₁ M - serum mucin | α1-Acid Glycoprotein, from human plasma | ORM1 | ORM | AGP1 | A1AG1 | AGP-A | HEL-S-153w

np001164-250μg

250μg

BioReagent

≥95%(SDS-PAGE)

Found in human plasma in concentrations of 55-140 mg per 100 ml. Classical standard glycoprotein for studies on the structure of the oligosaccharide units. Carbohydrate content is 40%. Its biological significance is unknown although it can bind progesterone 15 times as strongly as albumin. Sialic-acid-deficient alpha-1-AG has an affinity for vitamin B-12. Clinically, alpha 1 acid glycoprotein is an acute-phase reactant that together with haptoglobin is an indicator of acute inflammation. The alpha 1 acid glycoprotein:haptoglobin ratio is useful in studies of bone marrow disorders, hemolytic processes and metastases. Source material shown to be non-reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA required tests.

Functions as a transport protein in the blood stream. Binds various ligands in the interior of its beta-barrel domain. Also binds synthetic drugs and influences their distribution and availability in the body. Appears to function in modulating the activity of the immune system during the acute-phase reaction.

45 kDa

45 kDa

人(Human)