胰蛋白酶 来源于牛胰腺

Serine protease 1 | PRSS1

np225024-25g

25g

GMP

>450 USP U/mg powder

胰蛋白酶是一种丝氨酸蛋白水解酶。胰蛋白酶特异性严密，专一作用于由碱性氨基酸精氨酸及亮氨酸所组成的肽键。易溶于水，不溶于三氯甲烷、乙醇，乙醚和甘油，Ca2+对胰蛋白酶有保护和激活作用。 用途 临床外科用于各种炎症、溃疡、坏疽、创伤、痿孔引起的局部脓肿、水肿、血肿及毒蛇咬伤等症。外科用于治疗癣疥及其他皮肤疾患。内科用于脓胸、肺气肿、支气管炎、支气管喘息等症。一般肌内注射，也可注入胸腔或脓疡痿管空洞内，排脓洗涤，或喷雾吸入用于呼吸道疾患。 除此之外，治疗糖尿病引起的并发症，如肾炎等;治疗骨科疾病。 作为食品加工助剂切割大分子蛋白。 其水解蛋白的特性作为试剂广泛应用于生物、医药、食品等行业的研发、检测领域。 Trypsin is a kind of serine protein hydrolase, exclusive role in composed of alkaline amino acids arginine and leucine peptide bond, soluble in water, insoluble in chloroform, ethanol, ethyl ether, and glycerin, Ca2+ is protection for trypsin and activation function. Application As pharmaceutical raw materials manufacturing injection, infusion agent, sprays, clinical surgery used for all sorts of inflammation, ulcers, gangrene, an abscess caused by trauma, impotent, edema, hematoma and snake bites. Surgery for the treatment of tinea scabies and other skin disorders. Internal medicine for pyothorax, emphysema, bronchitis, bronchus wheeze, etc; Treatment of diabetic complications, such as nephritis; Treatment of bone disease. As a food processing cutting big molecular protein. As a proteolytic enzyme is widely applied in biology, medicine and food industries research and development, testing field.

Trypsin cleaves peptides on the C-terminal side of lysine and arginine residues. The rate of hydrolysis of this reaction is slowed if an acidic residue is on either side of the cleavage site and hydrolysis is stopped if a proline residue is on the carboxyl side of the cleavage site. The optimal pH for trypsin activity is 7-9. Trypsin can also act to cleave ester and amide linkages of synthetic derivatives of amino acids. EDTA is added to trypsin solutions as a chelating agent that neutralizes calcium and magnesium ions that obscure the peptide bonds on which trypsin acts. Removing these ions increases the enzymatic activity. Serine protease inhibitors, including DFP, TLCK, APMSF, AEBSEF, and aprotinin, amongst others, will inhibit Trypsin.

Trypsin >450 USP U/mg powder, Chymotrypsin <75 USP U/mg powder

天然

23.8 kDa

牛(Bovine)