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Product details

名称

Recombinant Human Activin RIA/ALK-2 Protein

别名

激活素A受体Ⅰ(ACVR1)重组蛋白 | 激活素A受体Ⅰ(ACVR1)重组蛋白

英文别名

货号

rp142507-10μg

包装规格

10μg

级别

无动物源

浓度

≥95%(SDS-PAGE)

生化机理

与配体结合后，形成由两个 II 型和两个 I 型跨膜丝氨酸/苏氨酸激酶组成的受体复合物。II 型受体磷酸化并激活 I 型受体，I 型受体自动磷酸化，然后结合并激活 SMAD 转录调节因子。活化素受体。可能参与胚胎发育过程中左右模式的形成。

生物活性

Measured by its binding ability in a functional ELISA. When Recombinant Human BMP-6 is used at 0.25 μg/mL, the concentration of Recombinant Human Activin RIA/ALK-2 Fc Chimera that produces 50% of the optimal binding response is found to be approximately 1-5 μg/mL.

预测分子量

39 & 28 kDa

蛋白标签

C-hFc & His

SDS-PAGE

40-45 kDa & 34-48 kDa, under reducing conditions

表达系统

HEK293 Accession #: Q04771 | HEK293

内毒素水平

<0.1 EU/μg

种属

人(Human)

氨基酸

23-124 aa & 120-124 aa

序列

DEKPKVNPKLYMCVCEGLSCGNEDHCEGQQCFSSLSINDGFHVYQKGCFQVYEQGKMTCKTPPSPGQAVECCQGDWCNRNITAQLPTKGKSFPGTQNFHLEVENLYFQGMDPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGKHHHHHH

无动物源

Yes

无载体

Yes

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

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