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Product details

名称

Recombinant Human Activin RIIA Protein

别名

激活素A受体ⅡA(ACVR2A)重组蛋白 | 重组人类激活素 RIIA 蛋白

英文别名

货号

rp142510-10μg

包装规格

10μg

级别

无动物源

浓度

≥95%(SDS-PAGE)

纯度

≥95% (SDS-PAGE)

产品介绍

Purity ≥95% (SDS-PAGE) Endotoxin level ＜0.1 EU/μg Function On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin A, activin B and inhibin A.

生物活性

Measured by its ability to inhibit Activin A-induced hemoglobin expression in K562 human chronic myelogenous leukemia cells. Approximately 0.01-0.05 μg/mL of Recombinant Human (rh) Activin RIIA Fc Chimera will inhibit 50% of the biological response due to 3 ng/mL of rhActivin A.

来源

重组表达

预测分子量

13 kDa

蛋白标签

C-His

SDS-PAGE

30.0 - 35.0 kDa, under reducing conditions; 30.0 - 35.0 kDa, under non-reducing conditions.

表达系统

HEK293 Accession #: P27037-1 | HEK293

内毒素水平

<0.1 EU/μg

种属

人(Human)

氨基酸

20-134 aa

序列

AILGRSETQECLFFNANWEKDRTNQTGVEPCYGDKDKRRHCFATWKNISGSIEIVKQGCWLDDINCYDRTDCVEKKDSPEVYFCCCEGNMCNEKFSYFPEMEVTQPTSNPVTPKPHHHHHH

无动物源

Yes

无载体

Yes

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

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