Recombinant Human BAFFR/TNFRSF13C Protein

重组人B-细胞激活因子受体蛋白 | 重组人 BAFFR/TNFRSF13C 蛋白

BAFF R | BAFFR | BR3 | CD268 | TNFRSF13C | CVID4 | BAFF-R | BROMIX | prolixin

rp143136-50μg

50μg

无动物源

≥95%(SDS-PAGE)

＞95%(SDS-PAGE)

Purity >95% SDS-PAGE. Function B Cell Activating Factor Receptor (BAFF-R), also named tumor necrosis factor receptor superfamily member 13C, is a member of the TNFR superfamily. It is highly expressed in spleen, lymph node, and resting B cells and to some extent in activated B cells, resting CD4+ cells and peripheral blood leukocytes. BAFF receptor is a type III transmembrane protein containing a single extracellular phenylalanine-rich domain and binds with high specificity to BAFF (TNFSF13B). It enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. BAFF receptor/BAFF signaling plays a critical role in B cell survival and maturation.

Fully biologically active when compared to standard. The ED50 as determined by its ability to block BAFF induced mouse splenocyte survival is 1.0-5.0 μg/ml in the presence of 1.0 μg/ml of rHuBAFF.

重组表达

7.8 kDa

No tag

Protein fragment

E. coli Accession #: Q96RJ3 | E. coli

<1.0 EU/μg

人(Human)

1-76 aa

MRRGPRSLRG RDAPAPTPCV PAECFDLLVR HCVACGLLRT PRPKPAGASS PAPRTALQPQ ESVGAGAGEA ALPLPG

Yes

Yes