Recombinant Human CCL14 Protein

重组人CCL14蛋白 | 重组人CCL14蛋白

CC-1 | CC-3 | CCL14 | CCL14_HUMAN | chemokine (C-C motif) ligand 14 | Chemokine CC-1/CC-3 | chemokine CC1 | chemokine CC3 | chemokine HCC1 | chemokine HCC3 | CKb1 | HCC 1 | HCC 3 | HCC-1(1-74) | HCC-1(9-74) | HCC-1/HCC-3 | HCC-3 | HCC1 | HEMOFILTRATE CC C

rp143727-50μg

50μg

无动物源

≥96%(SDS-PAGE&HPLC)

＞96%(SDS-PAGE and HPLC)

Purity > 96% by SDS-PAGE and HPLC analyses. Function Has weak activities on human monocytes and acts via receptors that also recognize MIP-1 alpha. It induced intracellular Ca(2+) changes and enzyme release, but no chemotaxis, at concentrations of 100-1,000 nM, and was inactive on T-lymphocytes, neutrophils, and eosinophil leukocytes. Enhances the proliferation of CD34 myeloid progenitor cells. The processed form HCC-1(9-74) is a chemotactic factor that attracts monocytes eosinophils, and T-cells and is a ligand for CCR1, CCR3 and CCR5. Post-translational The N-terminal processed forms HCC-1(3-74), HCC-1(4-74) and HCC-1(9-74) are produced in small amounts by proteolytic cleavage after secretion in blood. HCC-1(1-74), but not HCC-1(3-74) and HCC-1(4-74), is partially O-glycosylated; the O-linked glycan consists of one Gal-GalNAc disaccharide, further modified by two N-acetylneuraminic acids.

Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human monocytes is in a concentration of 5.0-20 ng/ml.

重组表达

8.4 kDa

No tag

Full length protein

E. coli Accession #: Q16627 | E. coli

<1.0 EU/μg

人(Human)

22-93 aa

TESSSRGPYH PSECCFTYTT YKIPRQRIMD YYETNSQCSK PGIVFITKRG HSVCTNPSDK WVQDYIKDMK EN

Yes

Yes