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Product details

名称

Recombinant Human CCL4/MIP-1 beta Protein

别名

重组人巨噬细胞炎性蛋白1β | 重组人 CCL4/MIP-1 beta 蛋白

英文别名

ACT2 | ACT-2 | AT744.1 | C-C motif chemokine 4 | CCL4 | chemokine (C-C motif) ligand 4 | Exodus-3 | G-26 T-lymphocyte-secreted protein | G-26 | HC21 | LAG1 | LAG-1 | Lymphocyte activation gene 1 protein | Macrophage inflammatory protein 1-beta | MIP1 beta

货号

rp143746-50μg

包装规格

50μg

级别

无动物源

浓度

≥96%(SDS-PAGE&HPLC)

纯度

＞96%(SDS-PAGE, HPLC)

产品介绍

Purity > 96 % by SDS-PAGE and HPLC analyses. Function Monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-beta(3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5-mediated entry of HIV-1 in T-cells. MIP-1-beta(3-69) is also a ligand for CCR1 and CCR2 isoform B.

生物活性

Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human peripheral blood monocytes is in a concentration range of 5.0-20 ng/ml.

来源

重组表达

预测分子量

7.8 kDa

蛋白标签

No tag

蛋白长度

Full length protein

表达系统

E. coli Accession #: P13236 | E. coli

内毒素水平

<1.0 EU/μg

种属

人(Human)

氨基酸

24-92 aa

序列

APMGSDPPTA CCFSYTARKL PRNFVVDYYE TSSLCSQPAV VFQTKRSKQV CADPSESWVQ EYVYDLELN

无动物源

Yes

无载体

Yes

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

user reviews

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