Recombinant Human CXCL5 Protein

上皮中性粒细胞激活肽78(ENA78)重组蛋白 | 重组人CXCL5蛋白 | 重组人 CXCL5 蛋白

chemokine (C-C motif) ligand 5 | C-X-C motif chemokine 5 | CXCL5 | CXCL5/ENA-78 | ENA78 | ENA-78 | ENA-78(1-78) | Epithelial-derived neutrophil-activating protein 78 | Neutrophil-activating peptide ENA-78 | neutrophil-activating protein 78 | SCYB5ENA78 |

rp144864-50μg

50μg

无动物源

≥97%(SDS-PAGE&HPLC)

＞97% (SDS-PAGE, HPLC)

CXCL5是一种小细胞因子，也被称为上皮中性粒细胞激活肽78(ena - 78)。这种蛋白质是在炎症细胞因子刺激细胞后产生的白细胞介素-1或肿瘤坏死因子。体外实验中，ENA-78(8-78)和ENA-78(9-78)使得中性粒细胞的趋化活性提高三倍。它们是由从外周血单核细胞分泌后的蛋白质水解产生的。重组人CXCL5 (5-78 a.a.)含有74个氨基酸，它是一个单一的非糖基化多肽链。人CXCL5有57%的氨基酸序列与小鼠和大鼠CXCL5相同。重组人ENA-78/CXCL5是一个8.1kDa大小的蛋白，含有74个氨基酸残基。 Purity >97% SDS-PAGE or HPLC analyses. Endotoxin level is Less than 0.1EU/µg . Function Involved in neutrophil activation. In vitro, ENA-78(8-78) and ENA-78(9-78) show a threefold higher chemotactic activity for neutrophil granulocytes. Post-translational N-terminal processed forms ENA-78(8-78) and ENA-78(9-78) are produced by proteolytic cleavage after secretion from peripheral blood monocytes. CXCL5 is a small cytokine also known as epithelial-derived neutrophil-activating peptide 78 (ENA-78). The protein is produced following stimulation of cells with the inflammatory cytokine interleukin-1 or tumor necrosis factor-alpha. In vitro, ENA-78 (8-78) and ENA-78 (9-78) show a threefold higher chemotactic activity for neutrophil granulocytes. They are produced by proteolytic cleavage after secretion from peripheral blood monocytes. Recombinant human CXCL5 (5-78 a.a.) contains 74 amino acids and it is a single non-glycosylated polypeptide chain. Human CXCL5 shares 57% amino acid sequence identity with mouse and rat CXCL5. Recombinant Human ENA-78/CXCL5 is an 8.1kDa protein containing 74 amino acid residues.

Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human peripheral blood neutrophils is in a concentration of 10.0-100.0 ng/ml.

重组表达

8.1 kDa

No tag

E. coli Accession #: P42830 | E. coli

<0.1 EU/μg

人(Human)

41-114 aa

AAVLRELRCVCLQTTQGVHPKMISNLQVFAIGPQCSKVEVVASLKNGKEICLDPEAPFLKKVIQKILDGGNKEN

Yes

Yes