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Product details

名称

Recombinant Human DR6/TNFRSF21 Protein

别名

重组人DR6/TNFRSF21蛋白 | 重组人肿瘤坏死因子受体超家族成员21蛋白

英文别名

货号

rp145276-10μg

包装规格

10μg

级别

无动物源

浓度

≥95%(SDS-PAGE)

纯度

≥95% (SDS-PAGE)

产品介绍

Purity ≥95% SDS-PAGE. Endotoxin level Function May activate NF-kappa-B and promote apoptosis. May activate JNK and be involved in T-cell differentiation. Required for both normal cell body death and axonal pruning. Trophic-factor deprivation triggers the cleavage of surface APP by beta-secretase to release sAPP-beta which is further cleaved to release an N-terminal fragment of APP (N-APP). N-APP binds TNFRSF21 triggering caspase activation and degeneration of both neuronal cell bodies (via caspase-3) and axons (via caspase-6).

生物活性

Immobilized Human APP at 10 μg/mL (100 μL/well) can bind Human DR6 with a linear range of 0.002-1.8 μg/mL.

来源

重组表达

预测分子量

65.5 kDa

蛋白标签

C-hFc & His

SDS-PAGE

95-100 kDa under reducing conditions

表达系统

HEK293 Accession #: O75509 | HEK293

内毒素水平

<0.1 EU/μg

种属

人(Human)

氨基酸

1-350 aa

序列

MGTSPSSSTALASCSRIARRATATMIAGSLLLLGFLSTTTAQPEQKASNLIGTYRHVDRATGQVLTCDKCPAGTYVSEHCTNTSLRVCSSCPVGTFTRHENGIEKCHDCSQPCPW

无动物源

Yes

无载体

Yes

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

user reviews

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