Recombinant human FGF1 protein

重组人FGF1蛋白

Acidic fibroblast growth factor | aFGF | ECGF | Endothelial cell growth factor | FGF-1 | HBGF-1 | Heparin-binding growth factor 1

rp145907-25μg

25μg

无动物源

≥95%(SDS-PAGE)

＞95% SDS-PAGE

Purity >95% as determined by SDS-PAGE and Coomassie blue staining Function The heparin-binding fibroblast growth factors play important roles in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. They are potent mitogens in vitro. Sequence similarities Belongs to the heparin-binding growth factors family. Cellular localization Secreted. Cytoplasm. Cytoplasm > cell cortex. Lacks a cleavable signal sequence. Within the cytoplasm, it is transported to the cell membrane and then secreted by a non-classical pathway that requires Cu(2+) ions and S100A13. Secreted in a complex with SYT1.

Measured in a cell proliferation assay using BALB/3T3 mouse embryo fibroblasts cell line in the presence of heparin. The ED₅₀ for this effect is typically <0.5ng/mL.

重组表达

15.9 kDa

No tag

Full length protein

E. coli Accession #: P05230 | E. coli

<0.1 EU/μg

人(Human)

16-155 aa

FNLPPGNYKKPKLLYCSNGGHFLRILPDGTVDGTRDRSDQHIQLQLSAES VGEVYIKSTE TGQYLAMDTDGLLYGSQTPNEECLFLERLEENHYNTYISKKHAEKNWFVG LKKNGSCKRG PRTHYGQKAILFLPLPVSSD

Yes

Yes