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Product details

名称

Recombinant Human IL-28 R alpha/IFN-lambda R1 Protein

别名

干扰素λ受体1重组蛋白 | 干扰素λ受体1重组蛋白

英文别名

货号

rp147537-10μg

包装规格

10μg

级别

无动物源

浓度

≥95%(SDS-PAGE)

产品介绍

Relevance IL-28RA is a class II cytokine receptor that interacts with IL10RB to bind IL28A, IL28B, and IL29, which are related to type I interferons. These ligands play a critical role in response to microbial challenge and activate the JAK/STAT signaling system. It heterodimers with IL10RB. There are 4 isoforms as result of alternative splicing. It is widely expressed. IL-28RA belongs to the type II cytokine receptor family, and contains 1 fibronectin type III domain.

生物活性

Measured by its binding ability in a functional ELISA. In a 100 μL reaction mixture containing rhIL-28 R alpha /Fc Chimera at 1 μg/mL and rhIL-28A dilutions at 1-1000 ng/mL, the concentration of rhIL-28A that produces 50% of the optimal binding response is found to be approximately 40-200 ng/mL.

来源

重组表达

预测分子量

51.5 kDa

蛋白标签

C-hFc & His

SDS-PAGE

70 kDa, under reducing conditions; 140 & 280 & 420 kDa, under non-reducing conditions.

表达系统

HEK293 Accession #: Q8IU57 | HEK293

内毒素水平

<0.1 EU/μg

种属

人(Human)

氨基酸

21-228 aa

序列

RPRLAPPQNVTLLSQNFSVYLTWLPGLGNPQDVTYFVAYQSSPTRRRWREVEECAGTKELLCSMMCLKKQDLYNKFKGRVRTVSPSSKSPWVESEYLDYLFEVEPAPPVLVLTQTEEILSANATYQLPPCMPPLDLKYEVAFWKEGAGNKTLFPVTPHGQPVQITLQPAASEHHCLSARTIYTFSVPKYSKFSKPTCFLLEVPEANWAENLYFQGMDPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGKHHHHHH

无动物源

Yes

无载体

Yes

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

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