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Product details

名称

Recombinant Human JAM-C Protein

别名

连接附着分子3(JAM3)重组蛋白

英文别名

JAM-2 | JAM-3 | JAM-C | Junctional adhesion molecule 3 | JAM-2 | CD323 | JAM3 | JAMC | JAM-C | JAM-CFLJ14529 | junctional adhesion molecule 3JAM-3 | junctional adhesion molecule C | JAM-3

货号

rp147885-10μg

包装规格

10μg

级别

无动物源

浓度

≥90%(SDS-PAGE)

产品介绍

Participates in cell-cell adhesion. It is a counterreceptor for ITGAM, mediating leukocyte-platelet interactions and is involved in the regulation of transepithelial migration of polymorphonuclear neutrophils (PMN). The soluble form is a mediator of angiogenesis.

生物活性

Measured by its ability to inhibit the adhesion of J45.01 human acute lymphoblastic leukemia T lymphocytes on immobilized JAM-2 (VE-JAM)/Fc Chimera. When 0.2 µg/mL (100 µL/well) of rhJAM-B/Fc Chimera is immobilized on goat anti-human IgG Fc Chimera antibody coated wells, the ED50 for this effect is 0.1-0.5 µg/mL in the presence of 1 x 10^5 cells/well.

来源

重组表达

预测分子量

51.8 kDa

蛋白标签

C-hFc & His

SDS-PAGE

60 - 65 kDa, under reducing conditions; 120 - 130 kDa, under non-reducing conditions.

表达系统

HEK293 Accession #: Q9BX67 | HEK293

内毒素水平

<0.1 EU/μg

种属

人(Human)

氨基酸

32-241 aa

序列

VNLKSSNRTPVVQEFESVELSCIITDSQTSDPRIEWKKIQDEQTTYVFFDNKIQGDLAGRAEILGKTSLKIWNVTRRDSALYRCEVVARNDRKEIDEIVIELTVQVKPVTPVCRVPKAVPVGKMATLHCQESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDSGQYYCIASNDAGSARCEEQEMEVYDLNENLYFQGMDPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGKHHHHHH

无动物源

Yes

无载体

Yes

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

user reviews

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