Recombinant Human Kallikrein 8/Neuropsin Protein

重组人Kallikrein 8/Neuropsin蛋白 | 重组人激肽释放酶8蛋白 | 重组人Kallikrein 8/Neuropsin蛋白 | 重组人激肽释放酶8蛋白 | 重组人Kallikrein 8/Neuropsin蛋白 | 重组人激肽释放酶8蛋白

EC 3.4.21.118 | hK8 | Neuropsin | NP | Ovasin | Serine protease 19 | Serine protease TADG-14 | Tumor-associated differentially expressed gene 14 protein | EC 3.4.21 | EC 3.4.21.118 | hK8 | HNP | kallikrein 8 (neuropsin/ovasin) | Kallikrein 8 | kallikrein-

rp147940-10μg

10μg

无动物源

≥95%(SDS-PAGE)

Function Serine protease which is capable of degrading a number of proteins such as casein, fibrinogen, kininogen, fibronectin and collagen type IV. Also cleaves L1CAM in response to increased neural activity. Induces neurite outgrowth and fasciculation of cultured hippocampal neurons. Plays a role in the formation and maturation of orphan and small synaptic boutons in the Schaffer-collateral pathway, regulates Schaffer-collateral long-term potentiation in the hippocampus and is required for memory acquisition and synaptic plasticity. Involved in skin desquamation and keratinocyte proliferation. Plays a role in the secondary phase of pathogenesis following spinal cord injury.

Measured by its ability to cleave the fluorogenic peptide substrate Boc-VPR-AMC. The specific activity is >500 pmol/min/µg, as measured under the described conditions.

重组表达

26 kDa

C-10His

31 - 37 kDa, under reducing conditions; 26 - 31 kDa, under non-reducing conditions.

HEK293 Accession #: O60259-1 | HEK293

<0.1 EU/μg

人(Human)

29-260 aa

QEDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKPKYTVRLGDHSLQNKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISLADHCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGSSKGADTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKIIGSKGHHHHHHHHHH

Yes

Yes