Recombinant Human XCL1 Protein

重组人淋巴细胞趋化因子(XCL1) | 重组人XCL1蛋白 | 重组人XCL1蛋白

ATAC | ATACSmall-inducible cytokine C1 | C motif chemokine 1 | chemokine (C motif) ligand 1 | Cytokine SCM-1 | LPTNSCM-1-alpha | LTNXC chemokine ligand 1 | Lymphotactin | lymphotaxin | SCM-1 alpha | SCM-1 | SCM1A | SCM-1a | SCYC1SCM1 | single cysteine mot

rp148449-50μg

50μg

无动物源

≥98%(SDS-PAGE&HPLC)

＞98%( SDS-PAGE and HPLC)

趋化因子(C基序)配体(XCL1)，被称为淋巴因子，是C趋化因子家族中唯一已知的成员，通过受体XCR1(正式名称为GPR5)发出信号。淋巴素在一些活化的T细胞中表达丰富，如活化的CD8+ T细胞和其他I类MHC限制性T细胞。在脾脏、胸腺、肠道和外周血白细胞中含量较高，在肺、前列腺和卵巢中含量较低。XCL1通过与一种叫做XCR1的趋化因子受体结合来诱导其趋化功能。重组人XCL1是一个含有92个氨基酸的单一非糖基化多肽链，它与小鼠和大鼠蛋白有大约60%的氨基酸序列同源性。 Purity >98% SDS-PAGE. purified using conventional chromatography techniques. Function Chemotactic activity for lymphocytes but not for monocytes or neutrophils. Chemokine (C motif) ligand (XCL1), as known as lymphotactin, is the only known member of the C-chemokine family and signals through the receptor XCR1, formally known as GPR5. The expression of lymphotactin is abundant in some activated T cells such as activated CD8+ T cells and other class I MHC restricted T cells. It is found in high levels in spleen, thymus, intestine and peripheral blood leukocytes, and at lower levels in lung, prostate gland and ovary. XCL1 induces its chemotactic function by binding to a chemokine receptor called XCR1. Recombinant Human XCL1 which is a single non-glycosylated polypeptide chains containing 92 amino acids and it shares approximately 60 % amino acid sequence homology with the murine and rat protein.

Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human T-lymphocytes is in a concentration of 10-100 ng/ml.

重组表达

10.2 kDa

No tag

10.2 kDa

Full length protein

E. coli Accession #: P47992 | E. coli

<1.0 EU/μg

人(Human)

23-114 aa

GSEVSDKRTC VSLTTQRLPV SRIKTYTITE GSLRAVIFITKRGLKVCADP QATWVRDVVRSMDRKSNTRN NMIQTKPTGTQQSTNTAVTL TG

Yes

Yes