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Product details

名称

Recombinant Human TGF-beta 1 Protein

别名

转化生长因子β1(TGFb1)活性蛋白 | 重组人类 TGF-β1 蛋白

英文别名

货号

rp152261-10μg

包装规格

10μg

级别

无动物源

浓度

≥95%(SDS-PAGE)

纯度

≥95% (SDS-PAGE)

产品介绍

Function Multifunctional protein that controls proliferation, differentiation and other functions in many cell types. Many cells synthesize TGFB1 and have specific receptors for it. It positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts.

生物活性

1、Measured by its ability to inhibit the IL-4-dependent proliferation of TF‑1 human erythroleukemic cells. The ED50 for this effect is 0.34 ng/mL in the presence of the 2.0 ng/mL Recombinant Mouse IL-4 Protein (rp154228). 2、Measured by its ability to inhibit the IL-4-dependent proliferation of HT‑2 mouse T cells. The ED50 for this effect is 35.9 ng/mL.

来源

重组表达

预测分子量

42 kDa

蛋白标签

N-8His

SDS-PAGE

13 & 42 & 55 kDa, under reducing conditions; 26 & 84 & 110 kDa, under non-reducing conditions.

表达系统

HEK293 Accession #: P01137 | HEK293

内毒素水平

<0.1 EU/μg

种属

人(Human)

氨基酸

30-390 aa (C33S)

序列

HHHHHHHHLSTSKTIDMELVKRKRIEAIRGQILSKLRLASPPSQGEVPPGPLPEAVLALYNSTRDRVAGESAEPEPEPEADYYAKEVTRVLMVETHNEIYDKFKQSTHSIYMFFNTSELREAVPEPVLLSRAELRLLRLKLKVEQHVELYQKYSNNSWRYLSNRLLAPSDSPEWLSFDVTGVVRQWLSRGGEIEGFRLSAHCSCDSRDNTLQVDINGFTTGRRGDLATIHGMNRPFLLLMATPLERAQHLQSSRHRRALDTNYCFSSTEKNCCVRQLYIDFRKDLGWKWIHEPKGYHANFCLGPCPYIWSLDTQYSKVLALYNQHNPGASAAPCCVPQALEPLPIVYYVGRKPKVEQLSNMIVRSCKCS

无动物源

Yes

无载体

Yes

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

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