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Product details

名称

Recombinant Human TNFRSF1A Protein

别名

重组人TNFRSF1A蛋白 | 重组人 TNFRSF1A 蛋白

英文别名

货号

rp152513-50μg

包装规格

50μg

级别

无动物源

浓度

≥97%(SDS-PAGE&HPLC)

纯度

＞97%(SDS-PAGE, HPLC)

产品介绍

Purity > 97 % by SDS-PAGE and HPLC analyses. Function Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase.

生物活性

Fully biologically active when compared to standard. The ED₅₀ as determined by its ability to inhibit the TNF-alpha mediated cytotoxicity in the L-929 cells is less than 0.05 μg/ml in the presence of 0.25 ng/mL of rHuTNF-alpha.

来源

重组表达

预测分子量

21.2 kDa

蛋白标签

No tag

蛋白长度

Protein fragment

表达系统

E. coli Accession #: P19438 | E. coli

内毒素水平

<0.1 EU/μg

种属

人(Human)

氨基酸

22-211 aa

序列

IYPSGVIGLV PHLGDREKRD SVCPQGKYIH PQNNSICCTK CHKGTYLYND CPGPGQDTDC RECESGSFTA SENHLRHCLS CSKCRKEMGQ VEISSCTVDR DTVCGCRKNQ YRHYWSENLF QCFNCSLCLN GTVHLSCQEK QNTVCTCHAG FFLRENECVS CSNCKKSLEC TKLCLPQIEN VKGTEDSGTT

无动物源

Yes

无载体

Yes

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

user reviews

Consultation

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