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Product details

名称

Recombinant Mouse FGF-21 Protein

别名

成纤维细胞生长因子21(FGF21)重组蛋白

英文别名

FGF21 | FGF-21 | fibroblast growth factor 21 | FGFL | PRO10196 | UNQ3115

货号

rp153968-10μg

包装规格

10μg

级别

无动物源

浓度

≥95%(SDS-PAGE)

生化机理

Stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression (but not SLC2A4/GLUT4 expression). Activity probably requires the presence of KLB. Regulates systemic glucose homeostasis and insulin sensitivity.

生物活性

Measured in a cell proliferation assay using NIH‑3T3 mouse embryonic fibroblast cells. The ED50 for this effect is 0.4-2 μg/mL in the presence of Recombinant Mouse Klotho beta.

来源

重组表达

预测分子量

20 kDa

蛋白标签

C-His

SDS-PAGE

22 kDa, under reducing conditions; 22 kDa, under non-reducing conditions.

表达系统

HEK293 Accession #: Q9JJN1 | HEK293

内毒素水平

<0.1 EU/μg

种属

小鼠(Mouse)

氨基酸

30-210 aa

序列

YPIPDSSPLLQFGGQVRQRYLYTDDDQDTEAHLEIREDGTVVGAAHRSPESLLELKALKPGVIQILGVKASRFLCQQPDGALYGSPHFDPEACSFRELLLEDGYNVYQSEAHGLPLRLPQKDSPNQDATSWGPVRFLPMPGLLHEPQDQAGFLPPEPPDVGSSDPLSMVEPLQGRSPSYASHHHHHH

无动物源

Yes

无载体

Yes

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

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