Recombinant mouse IL-7 protein

重组小鼠白细胞介素7蛋白 | 重组小鼠 IL-7 蛋白

IL7 | IL-7 | interleukin-7 | interleukin 7 | Lymphopoietin-1 | PBGF | hlb368 | A630026I06Rik

rp154245-2μg

2μg

无动物源

≥97%(SDS-PAGE)

＞97%(SDS-PAGE)

Purity >97% SDS-PAGE. Interleukin-7 (IL-7) is encoded by the IL7 gene in mouse and secreted by stromal cells in the red marrow and thymus. The protein signals through the IL-7 receptor, which is a heterodimer consisting of IL-7 receptor alpha and IL-2 receptor gamma chain. IL-7 stimulates the differentiation of hematopoietic stem cells into lymphoid progenitor cells and it can stimulate proliferation of B cells, T cells and NK cells. Mouse IL-7 has approximately 65 % and 88 % amino acid sequence identity with human and rat IL-7 and both proteins exhibit cross-species activity. Recombinant Mouse IL-7 is a 14.9kDa globular protein containing 129 amino acid residues. Function Hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation.

Measured in a cell proliferation assay using PHA-activated human peripheral blood mononuclear cell (PBMC). The ED50 for this effect is less than 1ng/mL。

重组表达

14.9 kDa

No tag

12.9 kDa, under reducing conditions; 12.1 kDa, under non-reducing conditions.

Full length protein

E. coli Accession #: Q544C8 | E. coli

<0.01 EU/μg

小鼠(Mouse)

26-154 aa

ECHIKDKEGKAYESVLMISIDELDKMTGTDSNCPNNEPNFFRKHVCDDTKEAAFLNRAARKLKQFLKMNISEEFNVHLLTVSQGTQTLVNCTSKEEKNVKEQKKNDACFLKRLLREIKTCWNKILKGSI

Yes

Yes

Glu-Cys-His-Ile-Lys-Asp-Lys-Glu