Recombinant Mouse TRANCE/RANKL/TNFSF11 Protein

重组小鼠 TRANCE/RANKL/TNFSF11 蛋白

CD254 antigen | CD254 | ODF | OPGL | OPGLOPTB2 | Osteoclast differentiation factor | Osteoprotegerin ligand | RANK L | RANKL | RANKLreceptor activator of nuclear factor kappa B ligand | Receptor activator of nuclear factor kappa-B ligand | sOdf | TNF-rela

rp154577-50μg

50μg

无动物源

≥95%(SDS-PAGE)

＞95%(SDS-PAGE)

Purity ＞95% SDS-PAGE. Actual molecular weight 19 kDa Additional sequence information Soluble Receptor Activator of NFkB Ligand Function Cytokine that binds to TNFRSF11B/OPG and to TNFRSF11A/RANK. Osteoclast differentiation and activation factor. Augments the ability of dendritic cells to stimulate naive T-cell proliferation. May be an important regulator of interactions between T-cells and dendritic cells and may play a role in the regulation of the T-cell-dependent immune response. May also play an important role in enhanced bone-resorption in humoral hypercalcemia of malignancy. Post-translational The soluble form of isoform 1 derives from the membrane form by proteolytic processing (By similarity). The cleavage may be catalyzed by ADAM17.

Measured by its ability to induce TRAP activity in Raw 264.7 cells.The ED50 of each lot is between 2-10 ng/mL.

重组表达

56kDa

N-Met & Fc

HEK293 Accession #: O35235 | HEK293

<0.01 EU/μg

小鼠(Mouse)

72-316 aa

MPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGKRAQMDPNRISEDSTHCFYRILRLHENADLQDSTLESEDTLPDSCRRMKQAFQGAVQKELQHIVGPQRFSGAPAMMEGSWLDVAQRGKPEAQPFAHLTINAASIPSGSHKVTLSSWYHDRGWAKISNMTLSNGKLRVNQDGFYYLYANICFRHHETSGSVPTDYLQLMVYVVKTSIKIPSSHNLMKGGSTKNWSGNSEFHFYSINVGGFFKLRAGEEISIQVSNPSLLDPDQDATYFGAFKVQDID

Yes

Yes