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Product details

名称

Recombinant Mouse SLAM/CD150 Protein

别名

重组小鼠SLAM/CD150蛋白 | 重组小鼠信号淋巴细胞激活分子家族成员1蛋白

英文别名

Signaling Lymphocytic Activation Molecule | CD 150 | CD150 | IPO-3 | CDw150 | signaling lymphocytic activation molecule family member 1 | SLAM | CD150 antigen | SLAMF1 | ESTM51 | 4933415F16

货号

rp154665-10μg

包装规格

10μg

级别

无动物源

浓度

≥95%(SDS-PAGE)

产品介绍

Function High-affinity self-ligand important in bidirectional T-cell to B-cell stimulation. SLAM-induced signal-transduction events in T-lymphocytes are different from those in B-cells. Two modes of SLAM signaling are likely to exist: one in which the inhibitor SH2D1A acts as a negative regulator and another in which protein-tyrosine phosphatase 2C (PTPN11)-dependent signal transduction operates.

生物活性

Measured by its ability to co-stimulate IL-4 secretion by D10.G4.1 mouse helper T cells in the presence of anti-CD3. The ED50 for this effect is 0.6-2.4 μg/mL.

来源

重组表达

预测分子量

25 kDa

蛋白标签

C-His

SDS-PAGE

41-55 kDa under reducing conditions.

表达系统

HEK293 Accession #: Q9QUM4-1 | HEK293

内毒素水平

<0.1 EU/μg

种属

小鼠(Mouse)

氨基酸

25-242 aa

序列

TGGGVMDCPVILQKLGQDTWLPLTNEHQINKSVNKSVRILVTMATSPGSKSNKKIVSFDLSKGSYPDHLEDGYHFQSKNLSLKILGNRRESEGWYLVSVEENVSVQQFCKQLKLYEQVSPPEIKVLNKTQENENGTCSLLLACTVKKGDHVTYSWSDEAGTHLLSRANRSHLLHITLSNQHQDSIYNCTASNPVSSISRTFNLSSQACKQESSSESSPHHHHHH

无动物源

Yes

无载体

Yes

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

user reviews

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