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Product details

名称

Recombinant Rat VEGF 164 Protein

别名

重组大鼠VEGF 164蛋白 | 重组大鼠血管内皮生长因子A蛋白

英文别名

货号

rp155249-10μg

包装规格

10μg

级别

无动物源

浓度

≥95%(SDS-PAGE)

产品介绍

Function Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. May play a role in increasing vascular permeability during lactation, when increased transport of molecules from the blood is required for efficient milk protein synthesis. Binding to NRP1 receptor initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development. Also binds the DEAR/FBXW7-AS1 receptor.

生物活性

Measured in a cell proliferation assay using HUVEC human umbilical vein endothelial cells. The ED50 for this effect is 0.75‑3.75 ng/mL.

来源

重组表达

预测分子量

19.2 kDa

蛋白标签

No tag

SDS-PAGE

22 - 28 kDa, under reducing conditions; 40 - 46 kDa, under non-reducing conditions.

表达系统

HEK293 Accession #: P16612-2 | HEK293

内毒素水平

<0.1 EU/μg

种属

大鼠(Rat)

氨基酸

27-190 aa

序列

APTTEGEQKAHEVVKFMDVYQRSYCRPIETLVDIFQEYPDEIEYIFKPSCVPLMRCAGCCNDEALECVPTSESNVTMQIMRIKPHQSQHIGEMSFLQHSRCECRPKKDRTKPENHCEPCSERRKHLFVQDPQTCKCSCKNTDSRCKARQLELNERTCRCDKPRR

无动物源

Yes

无载体

Yes

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

user reviews

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