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Product details

名称

Recombinant Human PDGF AA Protein

英文别名

PDGF1 | PDGF-A | PDGFAA | PDGF-AA

货号

rp156179-10μg

包装规格

10μg

级别

无载体

浓度

≥95%(SDS-PAGE)

生化机理

Platelet-derived growth factor alpha (PDGFA) is frequently upregulated in various cancers and thought to function as a key player in the development and progression of tumor growth by regulating aspects of cell proliferation, angiogenesis and metastasis. The human platelet-derived growth factor A chain gene (PDGFA) on chromosome 7p22 encodes an important mitogen. Within PDGFA lies a complex minisatellite structure that results in partial duplications of exon 4 and the IVS4 splice donor site.

生物活性

Measured in a cell proliferation assay using Balb/3T3 mouse embryonic fibroblast cells. The ED50 for this effect is 2.1 ng/mL.

来源

重组表达

预测分子量

14.3 kDa

蛋白标签

No tag

SDS-PAGE

17.3 kDa, under reducing conditions; 31.3 kDa, under non-reducing conditions.

表达系统

E. coli Accession #: P04085 | E. coli

内毒素水平

<1.0 EU/μg

种属

人(Human)

氨基酸

87-211 aa

序列

SIEEAVPAVCKTRTVIYEIPRSQVDPTSANFLIWPPCVEVKRCTGCCNTSSVKCQPSRVHHRSVKVAKVEYVRKKPKLKEVQVRLEEHLECACATTSLNPDYREEDTGRPRESGKKRKRKRLKPT

无动物源

无载体

Yes

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

user reviews

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