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Product details

名称

Recombinant Human Histone H2AX Protein

别名

重组人Histone H2AX蛋白 | 重组人类组蛋白 H2AX 蛋白

英文别名

货号

rp156659-1mg

包装规格

1mg

级别

无载体

浓度

≥90%(SDS-PAGE)

纯度

>90% (SDS-PAGE)

产品介绍

Purity:>90%, by SDS-PAGE visualized with Coomassie® Blue Staining. Description： Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C-terminal phosphorylation.

来源

重组表达

预测分子量

14.8 kDa

蛋白标签

N-His

SDS-PAGE

15.6 kDa, under reducing conditions; 15.6 kDa, under non-reducing condition

表达系统

E. coli Accession #: P16104 | E. coli

种属

人(Human)

氨基酸

1-130 aa

序列

MGHHHHHHMSGRGKTGGKARAKAKSRSSRAGLQFPVGRVHRLLRKGHYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGGVTIAQGGVLPNIQAVLLPKKTSATVGPKAP

无动物源

无载体

Yes

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

user reviews

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