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Product details
名称
Recombinant Human LR3 IGF-I/IGF-1 GMP Protein
别名
胰岛素样生长因子I重组蛋白 | 重组人 LR3 IGF-I/IGF-1 GMP 蛋白
英文别名
IBP1 | IGF1 | IGF-1 | IGF1A | IGFI | IGF-I | IGF-IA | IGF-IB | insulin-like growth factor 1 (somatomedin C) | insulin-like growth factor 1 | insulin-like growth factor I | insulin-like growth factor IA | insulin-like growth factor IB | IGF | somatomedin-C
货号
rp163958-GMP-200μg
包装规格
200μg
级别
无动物源
浓度
≥95%(SDS-PAGE&SEC-HPLC)
生化机理
从血浆中分离出来的胰岛素样生长因子在结构上和功能上与胰岛素有关,但具有更高的生长促进活性。可能是成骨细胞中[1-14C]-2-脱氧-D-葡萄糖(2DG)转运和糖原合成的生理调节剂。可刺激大鼠骨源性成骨细胞(PyMS)中的葡萄糖转运,其浓度远低于胰岛素,不仅在糖原和 DNA 合成方面有效,而且在提高葡萄糖摄取方面也有效。
生物活性
Measured in a serum-free cell proliferation assay using MCF7 human breast cancer cells. The ED50 for this effect is 0.3-1.5 ng/mL. IGFBP-3 does not inhibit its activity.
来源
重组表达
预测分子量
9 kDa
蛋白标签
No tag
SDS-PAGE
8 kDa, under reducing conditions
表达系统
E. coli Accession #: P05019.1 | E. coli
内毒素水平
<0.01 EU/μg
种属
人(Human)
氨基酸
49-118 aa (E51R)
序列
MFPAMPLSSLFVNGPRTLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPAKSA
无动物源
Yes
无载体
Yes
N-末端序列
Met-Phe-Pro-Ala-Met-Pro-Leu-Ser-Ser-Leu
Safety
「No Dangerous Attributes」
Related
「No upstream and downstream information yet」
Technical Documents
「No technical documents」
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「No related articles yet」
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Research chemical ≥95%; HPLC

Research chemical ≥95%; HPLC; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: ≥95%; HPLC.

item number:rp163958-GMP-200μg
Product model:200μg
level: ≥95%; HPLC
Lead Time:30days
sold 276 Items
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200μg

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