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Product details

名称

Recombinant Mouse IL-1Rrp2/IL-1R6 Protein

别名

白介素1受体样蛋白2(IL1RL2)重组蛋白

英文别名

货号

rp164643-10μg

包装规格

10μg

级别

无动物源

浓度

≥90%(SDS-PAGE)

生化机理

白细胞介素-36（IL36A、IL36B 和 IL36G）受体。与白细胞介素-36 结合后与核心受体 IL1RAP 结合形成白细胞介素-36 受体复合物，从而介导白细胞介素-36 依赖性激活 NF-kappa-B、MAPK 和其他通路。IL-36 信号系统被认为存在于上皮屏障中，并参与局部炎症反应；它与 IL-1 系统相似。似乎通过诱导 IL-23/IL-17/IL-22 途径参与皮肤炎症反应。

生物活性

Measured by its binding ability in a functional ELISA. Immobilized rmIL-1F5, rmIL-1F6, or rmIL-1F8 at 1 µg/mL (100 µL/well) can bind rmIL-1 Rrp2/his with a linear range of 0.078-5 µg/mL.

来源

重组表达

预测分子量

36.8 kDa

蛋白标签

C-His

SDS-PAGE

55-68 kDa, under reducing conditions

表达系统

HEK293 Accession #: Q9ERS7 | HEK293

内毒素水平

<0.1 EU/μg

种属

小鼠(Mouse)

氨基酸

22-338 aa (A158V)

序列

DTCEDIFMHNVIISEGQPFPFNCTYPPETNGAVNLTWYKTPSKSPVSNNRHLRVHQDQTWILFLPLTLEDSGIYQCVIRNAHNCYQIAVNLTVLKNHWCDSSMEGSPVNSPDVYQQILPIGKSGSLNCHLYFPESCVLDSIKWYKGCEEIKAGKKYSPSGAKLLVNNVAVEDGGSYACSARLTHLGRHFTIRNYIAVNTKEVEYGRRIPNITYPKNNSIEVPLGSTLIVNCNITDTKENTNLRCWRVNNTLVDDYYKDSKRIQEGIETNVSLRDQIRYTVNITFLKVKMEDYGRPFTCHAGVSAAYIILIYPVPDFRHHHHHH

无动物源

Yes

无载体

Yes

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

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