Recombinant Cotton Rat CD8 alpha Protein

重组棉鼠CD8 alpha蛋白 | 重组棉鼠CD8a分子蛋白

CD_antigen: CD8a | CD8 antigen, alpha polypeptide (p32) | CD8 | CD8a molecule | CD8A | Leu2 T-lymphocyte antigen | LEU2 | MAL | OKT8 T-cell antigen | p32 | T cell co-receptor | T8 T-cell antigen | T-cell antigen Leu2 | T-cell surface glycoprotein CD8 alph

rp165076-10μg

10μg

无动物源

≥90%(SDS-PAGE)

Background CD8 is a dimeric complex made up of two Ig superfamily members (1). The CD8 alpha chain is a type I transmembrane glycoprotein that can dimerize either with itself forming CD8 alpha alpha, or with a 30-35 kDa CD8 beta chain, forming CD8 alpha beta (2). CD8 alpha contains one V-type Ig-like domain in its extracellular region that binds to class I MHC molecules. CD8 alpha beta is a TCR co-receptor, while CD8 alpha alpha promotes T cell survival and differentiation (1, 3). The mature cotton rat CD8 alpha consists of a 159 amino acid (aa) extracellular domain (ECD), and runs at ~30 kDa under reduced condition. Within the ECD, cotton rat CD8 alpha shares 49%, 47%, and 54% amino acid sequence identity with human, mouse, and rat CD8 alpha, respectively.

Testing in progress

重组表达

18 kDa

C-His

26-32 kDa under reducing conditions.

HEK293 Accession #: Q8VH42 | HEK293

<0.1 EU/μg

大鼠(Rat)

24-182 aa

SKDFEMSPKKVVAHLGKEVRLTCEVWVSTSQGCSWLFLEHGSGVKPTFLIYLSGSRNERNNKIPSTKLSGKKEDKKYTLTLNNFAKEDEGYYFCSVTSNSVVYFSPLVSVFLPEKPTTPVPKPPTSVPTTAISRSLRPEACRPGAGTSVEKKGWDFDCDHHHHHH

Yes

Yes