Recombinant Mouse IL-31RA Protein

重组小鼠IL-31RA蛋白 | 重组小鼠白介素31受体A蛋白 | 重组小鼠IL-31RA蛋白 | 重组小鼠白介素31受体A蛋白

Interleukin 31 Receptor A | class I cytokine receptor | CRL3 | Glmr | Cytokine receptor-like 3 | GLMR | GLM-R | MGC125346 | GP130 like receptor | Gp130-like monocyte receptor | Gp130-like receptor | hGLM-R | IL-31 RA | IL-31 receptor subunit alpha | IL-31

rp165869-10μg

10μg

无动物源

≥95%(SDS-PAGE)

Function Associates with OSMR to form the interleukin-31 receptor which activates STAT3 and to a lower extent STAT1 and STAT5. May function in skin immunity. Mediates IL31-induced itch, probably in a manner dependent on cation channels TRPA1 and TRPV1. Positively regulates numbers and cycling status of immature subsets of myeloid progenitor cells in bone marrow in vivo and enhances myeloid progenitor cell survival in vitro.

Measured by its binding ability in a functional ELISA. When Recombinant Mouse IL‑31 RA Fc Chimera is immobilized at 5 µg/mL (100 µL/well), Recombinant Mouse IL‑31 binds with an ED50 of 0.9-5.4 μg/mL.

重组表达

83.4 kDa

C-hFc & His

110 - 130 kDa, under reducing conditions; 110 - 130 & 250 - 280 kDa, under non-reducing conditions.

HEK293 Accession #: Q8K5B1-1 | HEK293

<0.1 EU/μg

小鼠(Mouse)

19-503 aa

VLPTKPENISCVFYFDRNLTCTWRPEKETNDTSYIVTLTYSYGKSNYSDNATEASYSFPRSCAMPPDICSVEVQAQNGDGKVKSDITYWHLISIAKTEPPIILSVNPICNRMFQIQWKPREKTRGFPLVCMLRFRTVNSSHWTEVNFENCKQVCNLTGLQAFTEYVLALRFRFNDSRYWSKWSKEETRVTMEEVPHVLDLWRILEPADMNGDRKVRLLWKKARGAPVLEKTFGYHIQYFAENSTNLTEINNITTQQYELLLMSQAHSVSVTSFNSLGKSQEAILRIPDVHEKTFQYIKSMKAYIAEPLLVVNWQSSIPAVDTWIVEWLPEAAMSKFPALSWESVSQVTNWTIEQDKLKPFTCYNISVYPVLGHRVGEPYSIQAYAKEGTPLKGPETRVENIGLRTATITWKEIPKSARNGFINNYTVFYQAEGGKELSKTVNSHALQCDLESLTRRTSYTVWVMASTRAGGTNGVRINFKTLSISENLYFQGMDPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGKHHHHHH

Yes

Yes