Recombinant Human SIRP beta 1/CD172b Protein

信号调节蛋白β1(SIRPb1)重组蛋白 | 重组人 SIRP beta 1/CD172b 蛋白

CD172 antigen like family member B | CD172b | CD172b antigen | DKFZp686A05192 | Signal regulatory protein beta 1 | SIRP BETA 1 | SIRP beta 1 isoform 3 | SIRPB1 | SIRP-BETA-1

rp167082-50μg

50μg

无动物源

≥95%(SDS-PAGE)

≥95% (SDS-PAGE)

Purity ≥95% (SDS-PAGE) Endotoxin level ＜0.1 EU/μg Function The protein encoded by the SIRPß1 gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins which are known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. SIRPß1 was found to interact with TYROBP/DAP12, a protein bearing immunoreceptor tyrosine-based activation motifs. This protein was also reported to participate in the recruitment of tyrosine kinase SYK. Multiple transcript variants encoding different isoforms have been found for this gene.

When Recombinant Human SIRP beta 1/CD172b is immobilized at 1 µg/mL (100 µL/well), Recombinant Human SP‑D binds with an ED50 of 0.1-0.8 μg/mL

重组表达

38 kDa

C-His

55-60 kDa, under reducing conditions

HEK293 Accession #: O00241-1 | HEK293

<0.1 EU/μg

人(Human)

30-371 aa

EDELQVIQPEKSVSVAAGESATLRCAMTSLIPVGPIMWFRGAGAGRELIYNQKEGHFPRVTTVSELTKRNNLDFSISISNITPADAGTYYCVKFRKGSPDDVEFKSGAGTELSVRAKPSAPVVSGPAVRATPEHTVSFTCESHGFSPRDITLKWFKNGNELSDFQTNVDPAGDSVSYSIHSTARVVLTRGDVHSQVICEIAHITLQGDPLRGTANLSEAIRVPPTLEVTQQPMRAENQANVTCQVSNFYPRGLQLTWLENGNVSRTETASTLIENKDGTYNWMSWLLVNTCAHRDDVVLTCQVEHDGQQAVSKSYALEISAHQKEHGSDITHEAALAPTAPLHHHHHH

Yes

Yes