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Product details

名称

Recombinant Human IL-17RD/SEF Protein

别名

白介素17受体D(IL17RD)重组蛋白 | 白介素17受体D(IL17RD)重组蛋白

英文别名

货号

rp168081-10μg

包装规格

10μg

级别

无动物源

浓度

≥95%(SDS-PAGE)

生化机理

成纤维细胞生长因子介导的 Ras-MAPK 信号传导和 ERK 激活的反馈抑制剂。通过空间阻断活化的 ERK 的核转位而不抑制 ERK 的胞质磷酸化，从而调节核 ERK 信号通路。介导 JNK 激活，并可能参与细胞凋亡（相似）。可抑制 FGF 诱导的 FGFR1 酪氨酸磷酸化（相似）。可能在 GnRH 分泌神经元的命运规范的早期阶段发挥作用（相似）。抑制 TGFB 诱导的晶状体上皮细胞从上皮到间质的转变（相似）。

生物活性

Testing in progress

来源

重组表达

预测分子量

32 kDa

蛋白标签

C-His

SDS-PAGE

45 - 63 kDa, under reducing conditions; 45 - 63 kDa, under non-reducing conditions.

表达系统

HEK293 Accession #: Q8NFM7 | HEK293

内毒素水平

<0.1 EU/μg

种属

人(Human)

氨基酸

27-299 aa

序列

AGGSGRARGADTCGWRGVGPASRNSGLYNITFKYDNCTTYLNPVGKHVIADAQNITISQYACHDQVAVTILWSPGALGIEFLKGFRVILEELKSEGRQCQQLILKDPKQLNSSFKRTGMESQPFLNMKFETDYFVKVVPFPSIKNESNYHPFFFRTRACDLLLQPDNLACKPFWKPRNLNISQHGSDMQVSFDHAPHNFGFRFFYLHYKLKHEGPFKRKTCKQEQTTETTSCLLQNVSPGDYIIELVDDTNTTRKVMHYALKPVHSPWAGPIRHHHHHH

无动物源

Yes

无载体

Yes

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

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