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Product details

名称

Recombinant Human/Mouse/Rat Activin A GMP Protein

别名

英文别名

货号

rp168392-GMP-10μg

包装规格

10μg

级别

无动物源

浓度

≥97%(SDS-PAGE&SEC-HPLC)

生化机理

抑制素和激活素分别抑制和激活垂体分泌促性腺激素。抑制素/激活素根据其亚基组成的不同，参与调节多种功能，如下丘脑和垂体激素分泌、性腺激素分泌、生殖细胞发育和成熟、红细胞分化、胰岛素分泌、神经细胞存活、胚胎轴发育或骨骼生长。抑制素似乎与激活素的功能相反。

生物活性

Measured by its ability to induce hemoglobin expression in K562 human chronic myelogenous leukemia cells. The ED50for this effect is 0.2-1.2 ng/mL.The specific activity of Recombinant Human/Mouse/Rat Activin A is >1000 units/mg, which is calibrated against the human Activin A WHO reference standard (NIBSC code: 91/626).

来源

重组表达

预测分子量

13 kDa (monomer)

蛋白标签

No tag

SDS-PAGE

14 kDa, reducing conditions. 24 kDa, non-reducing conditions.

表达系统

CHO Accession #: P08476 | CHO

内毒素水平

<0.01 EU/μg

种属

人(Human)

氨基酸

311-426 aa

序列

GLECDGKVNICCKKQFFVSFKDIGWNDWIIAPSGYHANYCEGECPSHIAGTSGSSLSFHSTVINHYRMRGHSPFANLKSCCVPTKLRPMSMLYYDDGQNIIKKDIQNMIVEECGCS

无动物源

Yes

无载体

Yes

N-末端序列

Gly311-Leu-Glu-(Cys)-Asp-Gly-Lys-Val-Asn-Ile

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

user reviews

Consultation

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