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Product details

名称

Recombinant Human TGF-beta 1 GMP Protein

别名

重组人转化生长因子β1蛋白 | 重组人类 TGF-β1 GMP 蛋白

英文别名

货号

rp168406-GMP-10μg

包装规格

10μg

级别

无动物源

浓度

≥97%(SDS-PAGE&SEC-HPLC)

生化机理

TGFB1 是一种多功能蛋白质，可控制多种类型细胞的增殖、分化和其他功能。许多细胞都能合成 TGFB1，并有其特异性受体。它对许多其他生长因子具有正向和负向调节作用。它在骨重塑过程中发挥着重要作用，因为它是成骨细胞骨形成的强效刺激物，可引起成骨细胞的趋化、增殖和分化。

生物活性

Measured by its ability to inhibit the IL-4-dependent proliferation of HT‑2 mouse T cells. The ED50 for this effect is 0.04-0.2 ng/mL.The specific activity of recombinant human TGF-β1 GMP is >1.0 x 10^7 units/mg, which is calibrated against the human TGF‑β1 Standard (NIBSC code: 89/514).

来源

重组表达

预测分子量

12.8 kDa (monomer)

蛋白标签

No tag

SDS-PAGE

12 kDa, under reducing conditions. 24 kDa, under non-reducing conditions.

表达系统

CHO Accession #: P01137.2 | CHO

内毒素水平

<0.1 EU/μg

种属

人(Human)

氨基酸

279-390 aa

序列

ALDTNYCFSSTEKNCCVRQLYIDFRKDLGWKWIHEPKGYHANFCLGPCPYIWSLDTQYSKVLALYNQHNPGASAAPCCVPQALEPLPIVYYVGRKPKVEQLSNMIVRSCKCS

无动物源

Yes

无载体

Yes

N-末端序列

Ala-Leu-Asp-Thr-Asn-Tyr-(Cys)-Phe-Ser-Ser

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

user reviews

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