Recombinant Human CD14 Protein

重组人CD14蛋白 | 重组人 CD14 蛋白

CD14 molecule | CD14 antigen | CD14 | CD14_HUMAN | LPS-R | Mo2 | monocyte differentiation antigen CD14 | Myeloid cell-specific leucine-rich glycoprotein | Myeloid cell specific leucine rich glycoprotein | Monocyte differentiation antigen CD14 urinary form

rp169573-10μg

10μg

无动物源

≥90%(SDS-PAGE)

The cluster of differentiation (CD) system is commonly used as cell markers in immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. Cluster of differentiation 14 (CD14) is a member of the CD system. It takes its name from its inclusion in the CD molecule surface marker proteins. CD14 exists in two forms: a form anchored into the membrane or a soluble form. CD14 was found expressed in macrophages, neutrophil granulocyte and dendritic cells. The major function is to serve as a co-receptor (along with TLR4 and MD-2) for the bacterial lipopolysaccharide (LPS) and other pathogen-associated molecular patterns.

Immobilized Recombinant Human CD14 Protein (rp169573) at 1.0 μg/mL can bind Recombinant CD14 Antibody (Ab006698) with the EC50 of 5.7 ng/mL.

重组表达

38.1 kDa

C-His

39.2-53.0 kDa, under reducing conditions; 37.4-51.2 kDa, under non-reducing conditions

HEK293 Accession #: P08571 | HEK293

<1.0 EU/μg

人(Human)

1-352 aa

MERASCLLLLLLPLVHVSATTPEPCELDDEDFRCVCNFSEPQPDWSEAFQCVSAVEVEIHAGGLNLEPFLKRVDADADPRQYADTVKALRVRRLTVGAAQVPAQLLVGALRVLAYSRLKELTLEDLKITGTMPPLPLEATGLALSSLRLRNVSWATGRSWLAELQQWLKPGLKVLSIAQAHSPAFSCEQVRAFPALTSLDLSDNPGLGERGLMAALCPHKFPAIQNLALRNTGMETPTGVCAALAAAGVQPHSLDLSHNSLRATVNPSAPRCMWSSALNSLNLSFAGLEQVPKGLPAKLRVLDLSCNRLNRAPQPDELPEVDNLTLDGNPFLVPGTALPHEGSMNSGVVPACHHHHHH

Yes

Yes