Recombinant Human IL-33 Protein

重组人IL-33蛋白 | 重组人 IL-33 蛋白

C9orf26 | C9orf26chromosome 9 open reading frame 26 (NF-HEV) | DKFZp586H0523 | DVS27 | DVS27-related protein | IL1F11 | IL-1F11 | IL33 | IL-33 | interleukin 33 | Interleukin-1 family member 11 | interleukin-33 | NFHEV | NF-HEV | NF-HEVNFEHEV | Nuclear fac

rp169652-50μg

50μg

无载体

≥95%(SDS-PAGE)

>95%(SDS-PAGE)

Purity:>95%, by SDS-PAGE visualized with Coomassie® Blue Staining. Description： Interleukin 33 (IL-33), also known as DVS27 or NF-HEV (Nuclear Factor from High Endothelial Venules), is a pro-inflammatory protein and a chromatin-associated cytokine of the IL-1 family with high sequence and structural similarity to IL-1 and IL-18. IL-33 protein is expressed highly and rather selectively by high endothelial venule endothelial cells (HEVECs) in human tonsils, Peyer's patches, and lymph nodes. IL-33 protein has transcriptional regulatory properties, and the researches suggested that IL-33 is a dual-function protein that might act both as a cytokine and as an intracellular nuclear factor. As a type 2 cytokines, IL-33 protein also play a pivotal role in helminthic infection and allergic disorders.

Measured by its binding ability in a functional ELISA. Immobilized human IL-33 (rp169652) at 2 μg/mL can bind Etokimab (anti-IL-33) (Ab170468) with the EC50 of 20.97 ng/mL.

重组表达

18.1 kDa

No tag

16.3 kDa, reducing conditions; 16.3 kDa, non-reducing conditions

E. coli Accession #: O95760 | E. coli

<1.0 EU/μg

人(Human)

112-270 aa

GPSITGISPITEYLASLSTYNDQSITFALEDESYEIYVEDLKKDEKKDKVLLSYYESQHPSNESGDGVDGKMLMVTLSPTKDFWLHANNKEHSVELHKCEKPLPDQAFFVLHNMHSNCVSFECKTDPGVFIGVKDNHLALIKVDSSENLCTENILFKLSET

No

Yes