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Product details

名称

Recombinant Human TSLP Protein

别名

重组人TSLP蛋白 | 重组人 TSLP 蛋白

英文别名

货号

rp169653-50μg

包装规格

50μg

级别

无载体

浓度

≥95%(SDS-PAGE)

纯度

>95%(SDS-PAGE)

产品介绍

Purity:>95%, by SDS-PAGE visualized with Coomassie® Blue Staining. Description： Thymic stromal lymphopoietin (TSLP) is an interleukin 7 (IL-7)-like cytokine originally characterized by its ability to promote the activation of B cells and dendritic cells (DCs). Thymic stromal lymphopoietin (TSLP) is a cytokine expressed by epithelial cells, including keratinocytes, and is important in allergic inflammation. Subsequent studies have shown that TSLP promotes T helper type 2 (TH2) cell responses associated with immunity to some helminth parasites and the pathogenesis of many inflammatory diseases, including atopic dermatitis and asthma. TSLP can promote TH2 cytokine-associated inflammation by directly promoting the effector functions of CD4+ TH2 cells, basophils and other granulocyte populations while simultaneously limiting the expression of DC-derived proinflammatory cytokines and promoting regulatory T cell responses in peripheral tissues.

生物活性

Immobilized Recombinant Human TSLP Protein (rp169653) at 2.0 μg/mL can bind Tezepelumab (anti-TSLP) (Ab170833) with the EC50 of 18.04 ng/mL.

来源

重组表达

预测分子量

17.0 kDa

蛋白标签

N-His

SDS-PAGE

15.4 kDa, reducing conditions

表达系统

E. coli Accession #: Q969D9 | E. coli

内毒素水平

<1.0 EU/μg

种属

人(Human)

氨基酸

29-159 aa

序列

MGSSHHHHHHSSGLVPRGSYDFTNCDFEKIKAAYLSTISKDLITYMSGTKSTEFNNTVSCSNRPHCLTEIQSLTFNPTAGCASLAKEMFAMKTKAALAIWCPGYSETQINATQAMKKRRKRKVTTNKCLEQVSQLQGLWRRFNRPLLKQQ

无动物源

无载体

Yes

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

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Consultation

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