Recombinant Human 4-1BB Ligand/TNFSF9 Protein

重组人4-1BB Ligand/TNFSF9蛋白 | 重组人 4-1BB 配体/TNFSF9 蛋白

41BB Ligand | 4-1BB Ligand | 4-1BBL | 4-1BB-L | CD137L | homolog of mouse 4-1BB-L | receptor 4-1BB ligand | TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 | tumor necrosis factor ligand superfamily member 9

rp169691-50μg

50μg

无载体

≥95%(SDS-PAGE)

Purity:≥95%, by SDS-PAGE visualized with Coomassie® Blue Staining. Description： 4-1BB ligand is the high affinity ligand of 4-1BB, also known as CD137L or TNFSF9. It is shown to be a type II surface glycoprotein belonging to the TNF superfamily. Expression of 4-1BBL is restricted to APCs, such as dendritic cells, macrophages, and activated B cells. Members of the TNF-TNF receptor superfamily have been shown to play critical roles in regulating cellular activation, differentiation and apoptosis. Several studies have reported that 4-1BBL/4-1BB interaction provided a co-stimulatory signal to T cells, and increased T cell proliferation and cytokines production. In addition, 4-1BBL is involved in cancers, infectious diseases and autoimmune diseases.

Immobilized Recombinant Human 4-1BB/TNFRSF9 Protein (rp169624) at 2.0 μg/mL can bind Recombinant Human 4-1BB Ligand/TNFSF9 Protein (rp169691) with the EC50 of 6.053 ng/mL.​

重组表达

21.7 kDa

N-His

20.6 kDa, under reducing conditions; 20.6 kDa, under non-reducing conditions

E. coli Accession #: P41273 | E. coli

<1.0 EU/μg

人(Human)

71-254 aa

MGMKHHHHHHENLYFQGSREGPELSPDDPAGLLDLRQGMFAQLVAQNVLLIDGPLSWYSDPGLAGVSLTGGLSYKEDTKELVVAKAGVYYVFFQLELRRVVAGEGSGSVSLALHLQPLRSAAGAAALALTVDLPPASSEARNSAFGFQGRLLHLSAGQRLGVHLHTEARARHAWQLTQGATVLGLFRVTPEIPAGLPSPRSE

No

Yes