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Product details

名称

Recombinant Human CCL11/Eotaxin Protein

别名

重组人CCL11/Eotaxin蛋白 | 重组人 CCL11/Eotaxin 蛋白

英文别名

货号

rp170419-50μg

包装规格

50μg

级别

无载体

浓度

≥95%(SDS-PAGE)

纯度

>95% (SDS-PAGE)

产品介绍

Purity:>95%, by SDS-PAGE visualized with Coomassie® Blue Staining. Description ： CCL11 or chemokine (C-C motif) ligand 11 is a member of the chemokine (C-C motif) ligand family. Chemokin (C-C motif) ligand 11 is a member of the chemokine family. There are four members of the chemokine family: C-C kemokines, C kemokines, CXC kemokines and CX3C kemokines. The C-C kemokines have two cysteines nearby the amino terminus. There have been at least 27 distinct members of this subgroup reported for mammals, called C-C chemokine ligands (CCL)-1 to 28. Chemokines are a family of small chemotactic cytokines, or proteins secreted by cells. They share the same structure similarities such as small size, and the presence of four cysteine residues in conserved locations in order to form their 3-dimensional shape. Some of the chemokines are considered pro-inflammatory which can be induced to recruit cells of the immune system to a site of infection during an immune response, while others are considered homeostatic and are implied in controlling the migration of cells during normal processes of tissue maintenance and development. CCL11 is implicated in allergic responses through selectively recruiting eosinophils by inducing their chemotaxis. The effects of CCL11 are mediated by its binding to chemokine receptor. Increased CCL11 levels in blood plasma are associated with aging in mice.

生物活性

Testing in progress

来源

重组表达

预测分子量

8.4 kDa

蛋白标签

No tag

SDS-PAGE

11.4 kDa, under reducing conditions; 11.4 kDa, under non-reducing conditions

表达系统

E. coli Accession #: Q6I9T4 | E. coli

内毒素水平

<1.0 EU/μg

种属

人(Human)

氨基酸

24-97 aa

序列

GPASVPTTCCFNLANRKIPLQRLESYRRITSGKCPQKAVIFKTKLAKDICADPKKKWVQDSMKYLDQKSPTPKP

无动物源

无载体

Yes

N-末端序列

Gly24

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

user reviews

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