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Product details

名称

Recombinant Canine CD14 Protein

别名

重组狗CD14蛋白 | 重组犬CD14蛋白

英文别名

CD14 | CD14 molecule | Monocyte differentiation antigen CD14 | Myeloid cell-specific leucine-rich glycoprotein

货号

rp175909-50μg

包装规格

50μg

级别

无动物源

浓度

≥95%(SDS-PAGE)

纯度

>95% (SDS-PAGE)

产品介绍

Purity:>95%, by SDS-PAGE visualized with Coomassie® Blue Staining. Description： Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway. Binds electronegative LDL (LDL-) and mediates the cytokine release induced by LDL-.

来源

重组表达

预测分子量

38.8 kDa

蛋白标签

C-His

SDS-PAGE

49.6-56.9 kDa, under reducing conditions; 47.4-54.2 kDa, under non-reducing conditions

表达系统

HEK293 Accession #: A0A1S7J0A8 | HEK293

内毒素水平

<1.0 EU/μg

种属

狗(Canine)

氨基酸

1-373 aa

序列

MMRTPCLLLLLLPPVLCVSETSLEPCEVDDDDFRCFCNFTDPQPDWSSAFQCMIAVEVEIHGGGRSLEQFLKGADADPKQYADMVRALRLRRLTVASAQVPAVLVTAFLRALGYSRLKELTLQDLEVTGTPPPPPLEATGPALSTLTLRNVSWATGSAWLAELQRWLKPGLKVLNIAQAHSLAFSCARLRTFPALTTLDLSDNPGLGEHGLASALCPQKFPALQALVLRNAGMHTPNGVCAAMAVAGVQPRHLDLSHNSLRATAPGAPACVWPSALDSLNLSFSGLGQVPKGLPARLSVLDLRCNKLNREPRLEELPKVSNLTLDGNPFLDPEAPKYQENPTTSGVVPSCARSGLAVGMSGTLAVLQRVGGFAHHHHHH

无动物源

Yes

无载体

Yes

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

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