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Product details

名称

Recombinant Feline CD64 Protein

别名

重组猫CD64蛋白

英文别名

货号

rp175919-10μg

包装规格

10μg

级别

无动物源

浓度

≥95%(SDS-PAGE)

生化机理

High affinity immunoglobulin gamma Fc receptor I, also known as FCGR1 and CD64, is an integral membraneglycoprotein and a member of the immunoglobulin superfamily. CD64 is a high affinity receptor for the Fc region of IgG gamma and functions in both innate and adaptive immune responses. Receptors that recognize the Fc portion of IgG function in the regulation of immune response and are divided into three classes designated CD64, CD32, and CD16. CD64 is structurally composed of asignal peptidethat allows its transport to the surface of a cell, threeextracellularimmunoglobulin domainsof the C2-type that it uses to bind antibody, a hydrophobictransmembrane domain, and a short cytoplasmic tail. CD64 isconstitutivelyfound on only macrophages and monocytes, but treatment of polymorphonuclear leukocyteswith cytokines likeIFNγandG-CSFcan induce CD64 expression on these cells. The inactivation of the mouse CD64 resulted in a wide range of defects in antibody Fc-dependent functions. Mouse CD64 is an early participant in Fc-dependent cell activation and in the development of immune responses.

来源

重组表达

预测分子量

33.2 kDa

蛋白标签

C-His

SDS-PAGE

40.9-51.4 kDa, under reducing conditions; 40.4-50.4 kDa, under non-reducing conditions

表达系统

HEK293 Accession #: M3X2Q6 | HEK293

内毒素水平

<1.0 EU/μg

种属

猫(Feline)

氨基酸

1-288 aa

序列

MWLLTALLLWVPAGAQADLTKAVITLQPPWVSVFQEENITLWCEGPHLPGNSSTRWFLNGTAFQTLTPRYRIAAASISDTGEYRCQTGLSVPSDPVRLEIHRDWLLLQVQSRVFTEGEPLTLRCHGWKNKLVYNVVFYQNDKAFKFSPQNSEFTILKTSLSHNGIYHCSGMGRHRYTSPGVSITVKELFLAPVLKASLSLPLLEGHLVNLSCETKLLLQRPGLQLYFSFYTGSKTLMSRNTSSGYQILTAKREDSGLYWCEATTEDGSIVKRSPELELQVLGLQTPTPHHHHHH

无动物源

Yes

无载体

Yes

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

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