Share to

Details

Safety

Technical Documents

Articles

reviews

Consult

returns

Product details

名称

Recombinant Human Cytokeratin 19 Protein

别名

重组人Cytokeratin 19蛋白 | 重组人细胞角蛋白19 | 重组人Cytokeratin 19蛋白 | 重组人细胞角蛋白19 | 重组人细胞角蛋白19蛋白

英文别名

货号

rp175920-10μg

包装规格

10μg

级别

无载体

浓度

≥95%(SDS-PAGE)

生化机理

CYFRA 21-1 是细胞角蛋白（CK）19 的一个片段。CK现在被称为角蛋白，是包括支气管上皮细胞在内的上皮细胞细胞骨架（角蛋白丝）的主要结构元素，根据二维电泳测定的分子质量和等电点的差异，CK被分为20个亚型。由于凋亡级联调节器 Caspase 3 的蛋白酶活性增强，CK19 在肿瘤转化的上皮细胞中加速降解，碎片被释放到血液中。这导致血液中的 CYFRA 21-1 值升高，因为 CK19 片段能被两种单克隆抗体识别。参与肌纤维的组织。与 KRT8 一起，帮助将收缩装置与横纹肌肋膜上的肌营养不良蛋白连接起来。

生物活性

Testing in progress

来源

重组表达

预测分子量

44.9 kDa

蛋白标签

N-His

SDS-PAGE

43.6 kDa, under reducing conditions; 43.6 kDa, under non-reducing conditions

表达系统

E. coli Accession #: P08727 | E. coli

种属

人(Human)

氨基酸

2-400 aa

序列

MHHHHHHTSYSYRQSSATSSFGGLGGGSVRFGPGVAFRAPSIHGGSGGRGVSVSSARFVSSSSSGAYGGGYGGVLTASDGLLAGNEKLTMQNLNDRLASYLDKVRALEAANGELEVKIRDWYQKQGPGPSRDYSHYYTTIQDLRDKILGATIENSRIVLQIDNARLAADDFRTKFETEQALRMSVEADINGLRRVLDELTLARTDLEMQIEGLKEELAYLKKNHEEEISTLRGQVGGQVSVEVDSAPGTDLAKILSDMRSQYEVMAEQNRKDAEAWFTSRTEELNREVAGHTEQLQMSRSEVTDLRRTLQGLEIELQSQLSMKAALEDTLAETEARFGAQLAHIQALISGIEAQLGDVRADSERQNQEYQRLMDIKSRLEQEIATYRSLLEGQEDHYNNLSASKVL

无动物源

无载体

Yes

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

user reviews

Consultation

Warm reminder：

Because the manufacturer may temporarily adjust product specifications, prices, inventory, parameters and other information without notice, and there are differences in each user's consultation time and procurement needs, the platform reply content is only of reference value within a certain period. Sorry for the inconvenience caused to you, and thank you for your understanding and support! Please consult the online customer service for the latest details. Everything is subject to the real-time reply of the customer service.！

After Sales Services

Please check the quantity, appearance and product information in time when you receive the goods. In case of damage, wrong delivery, abnormal quality and other problems, please feel free to contact us.

Service Hotline:400-6226-992 ，We will handle it for you as soon as possible, thank you for your support and trust.！