Recombinant Canine CD64 Protein

重组狗CD64蛋白 | 重组犬CD64蛋白

High affinity IgG Fc gamma receptor 1 | Fc fragment of IgG receptor Ia | FcgammaRI | FCGR1A | FCG1 | FCGR1 | IGFR1 | CD64 | CD64A | FCRI

rp175923-1mg

1mg

无动物源

≥90%(SDS-PAGE)

>90% (SDS-PAGE)

Purity:>90%, by SDS-PAGE visualized with Coomassie® Blue Staining. Description： Receptors that recognize the Fc portion of IgG are divided into three groups designated Fc gamma RI, RII, and RIII, also known respectively as CD64, CD32, and CD16. Fc gamma RI binds IgG with high affinity and functions during early immune responses. Fc gamma RII and RIII are low affinity receptors that recognize IgG as aggregates surrounding multivalent antigens during late immune responses. High affinity immunoglobulin gamma Fc receptor I is also known as FCGR1A, FCG1, FCGR1, CD64 and IGFR1, is a type of integral membrane glycoprotein that binds monomeric IgG-type antibodies with high affinity, which belongs to the immunoglobulin superfamily or FCGR1 family. FCGR1A / CD64 contains 3 Ig-like C2-type (immunoglobulin-like) domains. CD64 is constitutively found on only macrophages and monocytes, but treatment of polymorphonuclear leukocytes with cytokines like IFNγ and G-CSF can induce CD64 expression on these cells.

重组表达

33.3 kDa

C-His

31.9-44.0 kDa, under reducing conditions; 30.8-40.6 kDa, under non-reducing conditions

HEK293 Accession #: Q7YQJ5 | HEK293

<1.0 EU/μg

狗(Canine)

1-288 aa

MWLLTVLLLWVPAGAQTDPVKAVITLQPPWVSVFQEESVTLWCEGPHLPGDSSTQWFLNGTATQTLTPRYRIAAASVNDNGEYRCQTGLSVLSDPIQLGIHRDWLILQVSGRVFTEGEPLTLRCHGWNNKLVYNVLFYQNGTVLKFSPQNSEFTILKTTLHHNGIYHCSAMGKHRYESAGVSITIKELFPAPVLKASLSSPILEGHVVNLSCETKLLLQRPGLQLYFSFYMGSKTLLSRNTSSEYQILTAKKEDSGLYWCEATTEDGNVVKRSPELELQVVGPQTLTPHHHHHH

Yes

Yes