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Product details

名称

Recombinant Human CCL24/Eotaxin-2/MPIF-2 Protein

别名

重组人CCL24/Eotaxin-2/MPIF-2蛋白 | 重组人 CCL24/Eotaxin-2/MPIF-2 蛋白

英文别名

货号

rp181317-10μg

包装规格

10μg

级别

无载体

浓度

≥95%(SDS-PAGE)

产品介绍

Protein Function:： CCL24, also known as Eotaxin-2 and MPIF-2, belongs to the intercrine beta (chemokine CC) family. CCL24 gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. CCL24 displays chemotactic activity on resting T lymphocytes, a minimal activity on neutrophils, and is negative on monocytes and activated T lymphocytes. CCL24 is also a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. CCL24 is chemotactic for resting T-lymphocytes, and eosinophils. It has lower chemotactic activity for neutrophils but none for monocytes and activated lymphocytes. It is a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. Eotaxin-2 interacts with chemokine receptor CCR3 to induce chemotaxis in eosinophils. Elevated level of Eotaxin-2 has been seen in patients with aspirin-exacerbated respiratory disease.

生物活性

Testing in progress

来源

重组表达

预测分子量

10.5 kDa

蛋白标签

No tag

SDS-PAGE

13.0 kDa, under reducing conditions; 25.0 kDa, under non-reducing conditions

表达系统

E. coli Accession #: O00175 | E. coli

内毒素水平

<1.0 EU/μg

种属

人(Human)

氨基酸

27-119 aa

序列

VVIPSPCCMFFVSKRIPENRVVSYQLSSRSTCLKGGVIFTTKKGQQFCGDPKQEWVQRYMKNLDAKQKKASPRARAVAVKGPVQRYPGNQTTC

无动物源

无载体

Yes

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

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