Recombinant Human Cardiotrophin-1/CT-1 Protein

重组人Cardiotrophin-1/CT-1 蛋白 | 重组人心肌营养素-1/CT-1 蛋白

cardiophin 1 | cardiotrophin 1 | Cardiotrophin1 | Cardiotrophin-1 | CT-1CT1 | CTF1

rp181570-10μg

10μg

无载体

≥95%(SDS-PAGE)

Protein Function: CTF1 is the first HOX11 protein partner identified that plays an important role in hematopoietic precursor cell immortalization. CTF1 was found to protect a gene from silencing when its DNA-binding sites were interposed between the gene and the telomeric extremity, while it did not affect a gene adjacent to the telomere. Protein fusions containing the CTF1 histone-binding domain displayed similar activities, while mutants impaired in their ability to interact with the histone did not. Cardiotrophin-1 (CTF1) has been reported to act as a trophic factor for a few neurons, such as sensory, cholinergic, dopaminergic, motor and cortical neurons. Studies have indicated that CTF1 delays degenerative disease progression in motor neuron disease.

Testing in progress

重组表达

21.1 kDa

No tag

22.3 kDa, under reducing conditions; 23.4 kDa, under non-reducing conditions

E. coli Accession #: Q16619 | E. coli

<1.0 EU/μg

人(Human)

2-201 aa

SRREGSLEDPQTDSSVSLLPHLEAKIRQTHSLAHLLTKYAEQLLQEYVQLQGDPFGLPSFSPPRLPVAGLSAPAPSHAGLPVHERLRLDAAALAALPPLLDAVCRRQAELNPRAPRLLRRLEDAARQARALGAAVEALLAALGAANRGPRAEPPAATASAASATGVFPAKVLGLRVCGLYREWLSRTEGDLGQLLPGGSA

No

Yes